Showing posts with label Pathology (Clinical). Show all posts
Showing posts with label Pathology (Clinical). Show all posts

Saturday, April 25, 2020

Pathology

SECTION 1/2: ANATOMICAL PATHOLOGY

The purpose I share my medical syllabus during my era is to help me know the topic should I revise during my free time to improve my medical knowledge and to give an idea for future medical students about the topic they would learn in medical school.

Topic of Anatomical Pathology discussed during my time in Medical School:

A. LECTURE:
1. 1st semester:
a. Basics Biology of Cells 1:
- Cell damage and cell death
- Inflammation
- Function of immune system to fight tumor and cancer
b. Basics Biology of Cells 3 (Diagnosis and Therapy/ Intervention at Cellular/ Molecular):
- Alteration of cell and tissue

2. 2nd semester:
a. Metabolism System:
- Pathology (anatomical) of organ affected by metabolism disorder of carbohydrate, lipid and protein and their interpretation

3. 3rd semester:
a. Reproductive system:
- Histological feature of benign tumor in female reproductive organ (vulva, vagina, cervix, uterus, oviduct, ovary, and breast)
- Histological feature of malignancy in female reproductive organ (vulva, vagina, cervix, uterus, oviduct, ovary, and breast)

4. 4th semester:
a. Dermatomusculoskeletal System:
- Features of skin disease
- Histopathological features of skin lesion
- Histopathological features of blistered skin disorder and skin growth
- Histopathology of infection and congenital disorder involving muscolo-skeletal system
- Histopathology of bone benign neoplasm
- Histopathology of bone malignancy
- Biopsy of bone tumor
b. Cardiovascular System:
- Blood vessel disease: Pathogenesis of arterial blood vessel disorder, pathogenesis of venous blood vessel disorder, pathogenesis of blood and lymphatic vessel tumor
- Heart disease: Pathogenesis types of heart disorder, pathogenesis of ischaemic heart disease, pathogenesis of heart infection, pathogenesis of pericardial disease
c. Respiratory System:
- Histopathology of respiratory system disorder: Histopathology changes of lung infection disease, pneumonia and obstructive pulmonary disease
- Lungs tumor: Metastatic tumor to lungs, carcinoma in lungs

5. 5th semester:
a. Genitourinary System:
- Pathology anatomical structure in genitourinary system disorder: Glomerular disease, tubulointerstitial disease, renal blood vessel disease, kidney cystic disease, kidney hydronephrosis disease
- Pathology of genitourinary system cancer: Tumor of kidney, urinary vesicle, prostate, testis, penis
b. Gastrointestinal System:
- Pathology of oral cavity disease: Pathology of Herpes stomatitis, oral thrush, acute necrotizing ulcerative gingivitis
- Pathology of tumor in oral cavity: Pathology of mucocele, pyogenic granuloma and benign squamous papilloma tumor, fibroma, lipoma, neurofibroma, hamangioma, oral cavity carcinoma
- Pathology of salivary gland disease: Pathology of sialolithiasis, parotiditis and Sjorgen syndrome, benign salivary gland tumor, pleomorphic tumor and arthin tumor, adenocarcinoma, mucoepidermoid carcinoma, adenoid cystic carcinoma
- Pathology of esophageal disease: anomaly of esophageal anatomy, pathology of inflammation of esophagus, esophagitis reflux, esophageal squamous cell carcinoma
- Pathology of stomach disease: Morphological difference of acute and chronic gastritis, pathology of gastric adeno carcinoma, gastric lymphoma
- Pathology of intestinal anomaly: Pathology of Hirsprung disease and congenital megacolon
- Pathology of intestinal blood vessel disorder: Pathology of Ischaemic bowel disease (IBS) and hemorrhoid
- Pathology of diarrheal related disease: Pathology of enterocolitis, malabsorption syndrome
- Pathology of Idiopathic inflammatory bowel disease: Pathology of Chron disease, ulcerative colitis
- Intestinal polyps: Pathology of non-neoplastic polyps and adenomatous polyps
- Intestinal tumor: Pathology of multiple polyposis syndrome, colorectal cancer, small intestine adenocarcinoma, carcinoid tumor, lymphoma
- Pathology of Hepatitis, liver failure, portal hypertension
- Pathology of Hepatic tumor: Pathology of hepatic hemangioma and adenoma, hepatocellular carcinoma, cholangiocarcinoma, hemangiosarcoma, metastatic tumor
- Pathology of obstructive bile tract: Pathology of Cholelithiasis, biliary colic, acute chocystitis and ascending cholangitis
- Gallbladder cancers: Pathology of adenocarcinoma of the gallbladder and adenocarcinoma of the extrahepatic biliary ducts
c. Special Senses System:
- Congenital eye disorder: Ocular albinism, pigmentous retinitis, x-linked coloboma
- Systemic disease related eye disease:  Exopthalmus in hyperthyroid disease, diabetic retinopathy, hypertensive retinopathy
- Pathogenesis of infective eye disease: Pathogenesis of conjunctivitis, pathogenesis and histopathology of herpes simplex related corneal disease
- Pathology of eye neoplasm: Pathology of malignant melanoma, retinoblastoma, intraocular and orbital metastatic tumor

6. 6th semester:
a. Brain and Mind System:
- Neoplasm of central nervous system: Primary neuroglial tumor (Glioma: Well deffirentiated astrocytoma, anaplastic astrocytoma, glioblastoma multiforme), primitive neuroepithelial neoplasm (medulloblastoma), neuronal neoplasm (ganglion cell tumor), benign tumor in nervous system (meningioma, hemangioblastoma)
- Primary disease of myelin (multiple sclerosis)
- Nervous system infection disease: Meningitis, encephalitis, viral encephalitis

7. 7th semester:
a. Elective (Viral-Oncogene):
- Cell proliferation and tumor growth: Differentiation and anaplastic, rates of growth cancer stem cells and cancer cell lineages
- Cell death: Necrosis and apoptosis, evasion of apoptosis, host defense again tumors-tumor immunity
- Tumor progression and metastasis: Cellular-molecular and micro environmental factors
- Angiogenesis
- Grading and staging of tumors
- Laboratory diagnosis of cancer


B. LABORATORY:
1. 1st semester:
a. Basics Biology of Cells 3 (Diagnosis and Therapy/ Intervention at Cellular/ Molecular):
- Management process of tissue specimen
- Microscopic image of tissue

2. 3rd semester:
a. Reproductive system:
- Uterine myoma and ovarian cyst
- Endometriosis and cervical cancer

3. 4th semester:
a. Dermatomusculoskeletal System:
- Dermatomusculoskeletal
b. Cardiovascular System:
- Histopathology changes in cardiovascular disease
c. Respiratory System:
- Sinonasal polyposis, nasopharyngeal carcinoma, tuberculosis lymphadenitis, lungs carcinoma

4. 5th semester:
a. Genitourinary System:
- Genitourinary system
b. Gastrointestinal System:
- Arrangement of digestive organ, liver and bile tract

5. 6th semester:
a. Brain and Mind System:
- Histopathology of nerve disorder

6. 7th semester:
a. Elective (Viral-Oncogene):
- Immunohistochemistry



*This medical syllabus copied and edited from 2 manual books for 1st semester medical student, 1 manual book for 2nd semester medical student, 1 manual book for 3rd semester medical student, 3 manual books for 4th semester medical student, 3 manual books for 5th semester medical student, 1 manual book for 6th semester medical student and 1 manual book for 7th semester medical student from my university during my era. 
**The topic currently discussed in my university may different from this syllabus due to progression of medical knowledge and improvement of quality for medical syllabus based on my university assessment.




SECTION 2/2: CLINICAL PATHOLOGY

The purpose I share my medical syllabus during my era is to help me know the topic should I revise during my free time to improve my medical knowledge and to give an idea for future medical students about the topic they would learn in medical school.

Topic of Clinical Pathology discussed during my time in Medical School:

A. LECTURE:
1. 1st semester:
a. Basics Biology of Cells 3 (Diagnosis and Therapy/ Intervention at Cellular/ Molecular):
- ELISA, PCR, and Electrophoresis
- Sampling the specimen
- Usage of anti-coagulant and specimen delivery

2. 2nd semester:
a. Metabolism System:
- Laboratory investigation and interpretation for metabolism disorder of carbohydrate, lipid and protein 
b. Hematological and Immunological System:
- Anemia: Classification and laboratory investigation of anemia
- Thalassemia
- Haemoglobinopathy
- Laboratory investigation for thalassemia and haemoglobinopathy
- Pathophysiology of haemostasis disorder: Coagulation and cascade of fibrinolysis
- Screening test of haemostasis disorder
- Blood malignancy: Classification and laboratory investigation for blood malignancy
- Blood bank and blood donation
- Immuno-haematological concept: Erythrocyte antigen, and plasma antibody
- Autoimmune disease: Basic principle and theory of autoimmune disease and laboratory investigation for autoimmune disease
- Immunodeficiency: Diagnostic test for HIV, AIDS (antibody, viral load, PCR and CD4)

3. 3rd semester:
a. Reproductive System:
- Functional disorder of female reproductive system: Interpretation of reproductive system hormones
b. Growth and Development:
- Common laboratory investigation (with its interpretation) done in neonate and infant 
- Laboratory investigation and interpretation for diagnosis of growth and development disorder

4. 4th semester:
a. Cardiovascular System:
- Hypercoagulable state in thromboembolism disorder
- Anti-coagulant and thrombolytic (fibrinolytic) therapy: Laboratory monitoring investigation for anti-platelet therapy, laboratory monitoring investigation for anti-coagulant therapy, laboratory monitoring investigation for IV Heparin and its derivative therapy, laboratory monitoring investigation for thrombolytic therapy, laboratory monitoring investigation for drugs used in percutaneous transluminal coronary angioplasty (PTCA) and stenting, laboratory monitoring investigation for drugs used in coronary artery bypass grafting (CABG), laboratory monitoring investigation for drugs used in open heart surgery
- Acute coronary event monitoring: Acute coronary event, transient ischaemic attack (TIA), reversible ischaemic neurological deficit, ischaemic stroke
- Antiphospholipid syndrome laboratory investigation: Sapporo criteria
- Catastrophic antiphospholipid syndrome: Taormina criteria
- Disseminated intravascular coagulation (DIC) and multiple organ failure
b. Respiratory System:
- Diagnostic laboratory investigation in respiratory disorder: Blood gas analysis
- Diagnostic laboratory investigation in pleural disorder: Pleural fluid analysis
- Diagnostic laboratory investigation in lower respiratory tract infection
- Pleural fluid analysis (laboratory topic)

5. 5th semester:
a. Genitourinary System:
- Renal function test to support clinical diagnosis of kidney function disorder
- Laboratory investigation in regulation of water, electrolytes, acid-base equilibrium
- Laboratory diagnostic investigation of sexually transmitted infection
b. Gastrointestinal System:
- Laboratory diagnostic investigation of liver and bile function disorder, hepatic cirrhosis, hepatoma, pancreatitis, pancreatic carcinoma, Hepatitis A-B-C

6. 6th semester:
a. Brain and Mind System:
- Cerebrospinal fluid (CSF) disorder: Cerebrospinal fluid analysis, changes of cerebrospinal fluid in bacterial-viral-fungal infection, changes of cerebrospinal fluid in subarachnoid hemorrhage-intracerebral hematoma-hypertensive encephalopathy-intracranial tumor-metabolic encephalopathy

7. 7th semester:
a. Tropical Medicine:
- Laboratory investigation in diagnosis of typhoid fever
- Laboratory investigation in diagnosis of dengue fever
- Laboratory investigation in diagnosis of HIV and AIDS
- Laboratory investigation in diagnosis of TORCH infection (Toxoplasmosis, Rubella, Cytomegalovirus, Herpes)
b. Family Medicine:
- Management of laboratory investigation: Management of laboratory referral, factors that affecting laboratory investigation result, improvement in laboratory internal quality
c. Elective (Viral-Oncogene):
- Laboratory test in oncology


B. LABORATORY:
1. 2nd semester:
a. Hematological and Immunological System:
- Diffential telling of leukocyte count
- ESR (Erythrocytes Sedimentation Rate), Hb Sahli, Hb Sian, MCV, Haematocrit test
- PT, aPTT, TT
- Leukocyte count and thrombocyte count

2. 3rd semester:
a. Reproductive System:
- Seminal fluid analysis and pregnancy test

3. 4th semester:
a. Respiratory System:

- Pleural fluid analysis

4. 5th semester:
a. Genitourinary System:
- Urinalysis
- Renal function
b. Gastrointestinal System:
- Transudative and exudative examination
- Stool examination

5. 7th semester:
a. Tropical Medicine:
- Rapid diagnostic tests


C. SKILLS LABORATORY (OSCE):
1. 3rd semester:
a. Growth and Development:
- Preparation of direct faecal smear specimen

2. 7th semester:
a. Tropical Medicine:
- Thick blood smear preparation




*This medical syllabus copied and edited from 1 manual books for 1st semester medical student, 2 manual books for 2nd semester medical student, 2 manual books for 3rd semester medical student, 2 manual books for 4th semester medical student, 2 manual books for 5th semester medical student, 1 manual book for 6th semester medical student and 3 manual books for 7th semester medical student from my university during my era. 
**The topic currently discussed in my university may different from this syllabus due to progression of medical knowledge and improvement of quality for medical syllabus based on my university assessment.

Tuesday, April 14, 2020

Basic Subjects For A Medical Student (Part 2a/7)

The purpose I share my medical syllabus during my era is to help me know the topic should I revise during my free time to improve my medical knowledge and to give an idea for future medical students about the topic they would learn in medical school.

Topic discussed during my 2nd Semester in Medical School:

A. CORE SUBJECTS:
1. Physiology:
a. Control System:
- Regulation of body system: Nervous system, endocrine system, respiratory system, urinary system, digestive system, reproductive system, integumentary system, immune system, muscular and skeletal system
- Physiology of central nervous system: Neuronal physiology, organization of the nervous system, cerebral cortex, cerebellum, basal nuclei, thalamus, hypothalamus
- Physiology of peripheral nervous system; Receptor physiology, autonomic nervous system, somatic nervous system
- Physiology of endocrine system:  Introduction (definition, classification, mechanism of action, control of secretion, mechanism of activation), general function of endocrine system (function of hypothalamic hormones, pituitary hormones, thyroid gland, parathyroid gland, pancreas, adrenal glands, testes and ovaries)
- Physiology of central nervous system (laboratory topic)
- Proprioceptive sensation (laboratory topic)
b. Metabolism System:
- Basic of Metabolism: Function and phases of metabolism
- Controlling hormones in metabolism and food intake: Hormones in regulation of carbohydrate, lipid and protein metabolism (epinephrine hormone, cortisol hormone, hypothalamus hormone, pituitary hormones, norepinephrine hormone, growth hormone, testosterone hormone) 
- Body temperature regulation
- Body temperature measurement
c. Hematological and Immunological System:
- Element of blood: Function of blood elements (function of erythrocyte, leukocyte, thrombocyte)
- Haemostasis: Physiology of haemostasis

2. Histology:
a. Control System:
- Histological structure of nerve tissue: Cells of the nervous tissue
- Histological structure of central and peripheral nervous system: Central nervous system, spinal cord, nerve regeneration, synapse, peripheral nerves
- Histological structure of endocrine organs: Hypophysis/ pituitary gland, adrenal gland, thyroid gland, parathyroid gland, pineal gland, pancreas (islets of Langerhans), gastrointestinal endocrine system
- Nerve tissue and nervous system (laboratory topic)
- Endocrine system (laboratory topic)
b. Hematological and Immunological System:
- Differentiation and maturation of hematopoietic system cells: Stem cell, erythropoietic, granulopoietic, thrombopoietic, lymphopoietic system
- Morphology of blood element (laboratory topic)
- Lymphoid organ (laboratory topic)

3. Anatomy:
a. Control System:
- Anatomical structure of central nervous system: Medulla spinal, cerebellum, diencephalon, telencephalon, blood vessel of central nervous system, cerebrospinal fluid system
- Anatomical structure of peripheral nervous system: Spinal nerve, vegetative nervous system
- Anatomical structure of endocrine organs: Hypophysis, pituitary, thyroid gland, parathyroid gland, pineal gland, pancreas, adrenal gland
- Nervous system (laboratory topic)
- Endocrine system (laboratory topic)

4. Pharmacology:
a. Control System:
- Basic of Pharmacology: Drugs and its problems, absorption, distribution, bio-transformation, excretion, dosage-response relationship, clinical pharmacokinetic, drug level monitoring, non-therapeutic drug effect, factors that influencing pharmacology of drug, pharmacokinetic interaction, pharmacodynamic interaction, cascade of drug transcription, pharmacoeconomy, drug prescription matters
- Pharmacology of central nervous system
- Pharmacology of peripheral nervous system
- Pharmacology of endocrine system
- Posology of drug (laboratory topic)
- Writing technique of drug transcription (laboratory topic)
- Unmixed drugs interaction (laboratory topic)
b. Metabolism System:
- Pharmacology of the endocrine pancreas
- Pharmacology of thyroid gland
- Pharmacology of adrenal cortex
- Pharmacology of the hypothalamus and pituitary gland
- Metabolism of salicylic drug (laboratory topic)
- Calculation of drug dosage (laboratory topic)
c. Hematological and Immunological System:
- Medications used in anemia: Oral iron supplementation and hematopoietic growth factors
- Medications used in bleeding and coagulation disorder: Anti-coagulation agent, fibrinolysis agent, anti-platelet agent, anti-thrombus agents, anti-hemorrhagic agent
- Medication that cause hemostasis disturbance
- Medications used in blood malignancy: Cytostatic drugs
- Immunopharmacology: Immunomodulator (basic concept of immunomodulator agents, antibodies as immuno-suppressive drugs, immunomodulating agents-cytokines), medications that (may) cause allergic and hypersensitivity reaction (NSAIDs, Antibiotic, etc.)

5. Biochemistry:
a. Metabolism System:
- Metabolism reaction pathways: Carbohydrate metabolism, lipid metabolism, amino acids metabolism, nucleotide metabolism, interaction of multiple metabolic reaction pathways, metabolites and end products in blood
- Controlling hormones in metabolism and food intake: Hormones in regulation of carbohydrate, lipid and protein metabolism (insulin, glucagon, thyroid hormone)
- Blood sugar level analysis (laboratory topic)
- Total blood protein level analysis (laboratory topic)
- Blood urea level analysis (laboratory topic)
b. Hematological and Immunological System:
- Element of blood: Hemoglobin

6. Nutrition:
a. Metabolism System:
- Food intake disorders: Anorexia nervosa, bulimia nervosa, binge, starvation, malnutrition (marasmus and kwashiorkor)
- Obesity
- Basic nutrition
- Weight management
- Nutritional care in Diabetes Mellitus
b. Hematological and Immunological System:
- Nutritional approach in nutritional deficiencies anemia

7. Endocrinology:
a. Metabolism System:
- Insulin hormone disorder: Insulin resistance
- Diabetes Mellitus
- Hypoglycemia
- Obesity
- Dyslipidemia
- Thyroid hormone disorders: Hyperthyroid, hypothyroid, thyroid tumor
- Adrenal hormone disorders: Cushing disease, Addison disease, Pheocromositoma
- Hypophysis disorder: Acromegaly, diabetes insipidus, Hypopituitary
- History taking of metabolic disorder cases, vital signs, Body Mass Index (BMI) (skills laboratory topic)

8. Pathology (Clinical):
a. Metabolism System:
- Laboratory investigation and interpretation for metabolism disorder of carbohydrate, lipid and protein 
b. Hematological and Immunological System:
- Anemia: Classification and laboratory investigation of anemia
- Thalassemia
- Haemoglobinopathy
- Laboratory investigation for thalassemia and haemoglobinopathy
- Pathophysiology of haemostasis disorder: Coagulation and cascade of fibrinolysis
- Screening test of haemostasis disorder
- Blood malignancy: Classification and laboratory investigation for blood malignancy
- Blood bank and blood donation
- Immuno-haematological concept: Erythrocyte antigen, and plasma antibody
- Autoimmune disease: Basic principle and theory of autoimmune disease and laboratory investigation for autoimmune disease
- Immunodeficiency: Diagnostic test for HIV, AIDS (antibody, viral load, PCR and CD4)
- Diffential telling of leukocyte count (laboratory topic)
- ESR (Erythrocytes Sedimentation Rate), Hb Sahli, Hb Sian, MCV, Haematocrit test (laboratory test)
- PT, aPTT, TT (laboratory topic)
- Leukocyte count and thrombocyte count (laboratory topic)

9. Pathology (Anatomical):
a. Metabolism System:
- Pathology (anatomical) of organ affected by metabolism disorder of carbohydrate, lipid and protein and their interpretation

10. Physics:
a. Control System:
- Control theory in biological systems
b. Metabolism System: - Body temperature regulation
- Body temperature measurement
- Calorimeter (laboratory topic)
- Types of thermometer and their usage, body and skin temperature measurement (laboratory topic)
c. Hematological and Immunological System:
- Stokes Law (Erythrocytes Sedimentation Rate test) (laboratory topic)

11. Immunology and Haematology:
a. Hematological and Immunological System:
- Anemia: Aplastic anemia in adult, nutritional deficiency anemia in adult, haemolytic anemia in adult, anemia of chronic disease in adult 
- Bleeding disorders in adult: ITP, and DIC
- Coagulation disorders in adult: Thrombosis (DVT, and Pulmonary embolism)
- MPD (Myeloproliferative Disorder) in adult
- MDS (Myelodysplastic Syndrome) in adult
- Leukemia in adult
- Lymphoma in adult
- Blood transfussion in adult
- Hypersensitivity reaction
- Autoimmune disease in adult: Types of autoimmune diseases (SLE, DM type 1, Hashimoto disease, Grave disease, Myastenia Gravis)
- Immunodeficiency: Basic concept of immunopathogenesis immunodeficiency
- Secondary immunodeficiency in adult: HIV/ AIDS
- Preparing peripheral blood smear (skills laboratory topic)
- ABO and rhesus blood grouping technique (skills laboratory topic)
- Bleeding time and rumple leed test (skills laboratory topic)

12. Pediatrics:
a. Hematological and Immunological System:
- Anemia: Aplastic anemia in children, nutritional deficiency anemia in children, haemolytic anemia in children, anemia of chronic disease in children
- Clinical diagnostic for Thalassemia
- Clinical diagnostic for Haemoglobinopathy
- Bleeding disorders in children: ITP, Neonatal thrombocytopenia, and DIC
- Coagulation disorders in children: Hemophilia, and thrombosis
- MDS (Myelodysplastic Syndrome) in children
- Leukemia in children
- Lymphoma in children
- Blood transfusion in children
- Autoimmune disease in children: Types of autoimmune diseases (SLE, JRA)
- Primary immunodeficiency in children
- Secondary immunodeficiency in children: MTCT (Mother to Child Transmission), AIDS
- Immunization: Concept and basic principle of Vaccinology


*This medical syllabus copied and edited from 3 manual books for 2nd semester medical student from my university during my era. 
**The topic currently discussed for 2nd semester medical student in my university may different from this syllabus due to progression of medical knowledge and improvement of quality for medical syllabus based on my university assessment.