Tuesday, April 14, 2020

Basic Subjects For A Medical Student (Part 2a/7)

The purpose I share my medical syllabus during my era is to help me know the topic should I revise during my free time to improve my medical knowledge and to give an idea for future medical students about the topic they would learn in medical school.

Topic discussed during my 2nd Semester in Medical School:

A. CORE SUBJECTS:
1. Physiology:
a. Control System:
- Regulation of body system: Nervous system, endocrine system, respiratory system, urinary system, digestive system, reproductive system, integumentary system, immune system, muscular and skeletal system
- Physiology of central nervous system: Neuronal physiology, organization of the nervous system, cerebral cortex, cerebellum, basal nuclei, thalamus, hypothalamus
- Physiology of peripheral nervous system; Receptor physiology, autonomic nervous system, somatic nervous system
- Physiology of endocrine system:  Introduction (definition, classification, mechanism of action, control of secretion, mechanism of activation), general function of endocrine system (function of hypothalamic hormones, pituitary hormones, thyroid gland, parathyroid gland, pancreas, adrenal glands, testes and ovaries)
- Physiology of central nervous system (laboratory topic)
- Proprioceptive sensation (laboratory topic)
b. Metabolism System:
- Basic of Metabolism: Function and phases of metabolism
- Controlling hormones in metabolism and food intake: Hormones in regulation of carbohydrate, lipid and protein metabolism (epinephrine hormone, cortisol hormone, hypothalamus hormone, pituitary hormones, norepinephrine hormone, growth hormone, testosterone hormone) 
- Body temperature regulation
- Body temperature measurement
c. Hematological and Immunological System:
- Element of blood: Function of blood elements (function of erythrocyte, leukocyte, thrombocyte)
- Haemostasis: Physiology of haemostasis

2. Histology:
a. Control System:
- Histological structure of nerve tissue: Cells of the nervous tissue
- Histological structure of central and peripheral nervous system: Central nervous system, spinal cord, nerve regeneration, synapse, peripheral nerves
- Histological structure of endocrine organs: Hypophysis/ pituitary gland, adrenal gland, thyroid gland, parathyroid gland, pineal gland, pancreas (islets of Langerhans), gastrointestinal endocrine system
- Nerve tissue and nervous system (laboratory topic)
- Endocrine system (laboratory topic)
b. Hematological and Immunological System:
- Differentiation and maturation of hematopoietic system cells: Stem cell, erythropoietic, granulopoietic, thrombopoietic, lymphopoietic system
- Morphology of blood element (laboratory topic)
- Lymphoid organ (laboratory topic)

3. Anatomy:
a. Control System:
- Anatomical structure of central nervous system: Medulla spinal, cerebellum, diencephalon, telencephalon, blood vessel of central nervous system, cerebrospinal fluid system
- Anatomical structure of peripheral nervous system: Spinal nerve, vegetative nervous system
- Anatomical structure of endocrine organs: Hypophysis, pituitary, thyroid gland, parathyroid gland, pineal gland, pancreas, adrenal gland
- Nervous system (laboratory topic)
- Endocrine system (laboratory topic)

4. Pharmacology:
a. Control System:
- Basic of Pharmacology: Drugs and its problems, absorption, distribution, bio-transformation, excretion, dosage-response relationship, clinical pharmacokinetic, drug level monitoring, non-therapeutic drug effect, factors that influencing pharmacology of drug, pharmacokinetic interaction, pharmacodynamic interaction, cascade of drug transcription, pharmacoeconomy, drug prescription matters
- Pharmacology of central nervous system
- Pharmacology of peripheral nervous system
- Pharmacology of endocrine system
- Posology of drug (laboratory topic)
- Writing technique of drug transcription (laboratory topic)
- Unmixed drugs interaction (laboratory topic)
b. Metabolism System:
- Pharmacology of the endocrine pancreas
- Pharmacology of thyroid gland
- Pharmacology of adrenal cortex
- Pharmacology of the hypothalamus and pituitary gland
- Metabolism of salicylic drug (laboratory topic)
- Calculation of drug dosage (laboratory topic)
c. Hematological and Immunological System:
- Medications used in anemia: Oral iron supplementation and hematopoietic growth factors
- Medications used in bleeding and coagulation disorder: Anti-coagulation agent, fibrinolysis agent, anti-platelet agent, anti-thrombus agents, anti-hemorrhagic agent
- Medication that cause hemostasis disturbance
- Medications used in blood malignancy: Cytostatic drugs
Immunopharmacology: Immunomodulator (basic concept of immunomodulator agents, antibodies as immuno-suppressive drugs, immunomodulating agents-cytokines), medications that (may) cause allergic and hypersensitivity reaction (NSAIDs, Antibiotic, etc.)

5. Biochemistry:
a. Metabolism System:
- Metabolism reaction pathways: Carbohydrate metabolism, lipid metabolism, amino acids metabolism, nucleotide metabolism, interaction of multiple metabolic reaction pathways, metabolites and end products in blood
- Controlling hormones in metabolism and food intake: Hormones in regulation of carbohydrate, lipid and protein metabolism (insulin, glucagon, thyroid hormone)
- Blood sugar level analysis (laboratory topic)
- Total blood protein level analysis (laboratory topic)
- Blood urea level analysis (laboratory topic)
b. Hematological and Immunological System:
- Element of blood: Hemoglobin

6. Nutrition:
a. Metabolism System:
- Food intake disorders: Anorexia nervosa, bulimia nervosa, binge, starvation, malnutrition (marasmus and kwashiorkor)
- Obesity
- Basic nutrition
- Weight management
- Nutritional care in Diabetes Mellitus
b. Hematological and Immunological System:
- Nutritional approach in nutritional deficiencies anemia

7. Endocrinology:
a. Metabolism System:
- Insulin hormone disorder: Insulin resistance
- Diabetes Mellitus
- Hypoglycemia
- Obesity
- Dyslipidemia
- Thyroid hormone disorders: Hyperthyroid, hypothyroid, thyroid tumor
- Adrenal hormone disorders: Cushing disease, Addison disease, Pheocromositoma
- Hypophysis disorder: Acromegaly, diabetes insipidus, Hypopituitary
- History taking of metabolic disorder cases, vital signs, Body Mass Index (BMI) (skills laboratory topic)

8. Pathology (Clinical):
a. Metabolism System:
- Laboratory investigation and interpretation for metabolism disorder of carbohydrate, lipid and protein 
b. Hematological and Immunological System:
- Anemia: Classification and laboratory investigation of anemia
- Thalassemia
- Haemoglobinopathy
- Laboratory investigation for thalassemia and haemoglobinopathy
- Pathophysiology of haemostasis disorder: Coagulation and cascade of fibrinolysis
- Screening test of haemostasis disorder
- Blood malignancy: Classification and laboratory investigation for blood malignancy
- Blood bank and blood donation
- Immuno-haematological concept: Erythrocyte antigen, and plasma antibody
- Autoimmune disease: Basic principle and theory of autoimmune disease and laboratory investigation for autoimmune disease
- Immunodeficiency: Diagnostic test for HIV, AIDS (antibody, viral load, PCR and CD4)
- Diffential telling of leukocyte count (laboratory topic)
- ESR (Erythrocytes Sedimentation Rate), Hb Sahli, Hb Sian, MCV, Haematocrit test (laboratory test)
- PT, aPTT, TT (laboratory topic)
- Leukocyte count and thrombocyte count (laboratory topic)

9. Pathology (Anatomical):
a. Metabolism System:
- Pathology (anatomical) of organ affected by metabolism disorder of carbohydrate, lipid and protein and their interpretation

10. Physics:
a. Control System:
- Control theory in biological systems
b. Metabolism System: - Body temperature regulation
- Body temperature measurement
- Calorimeter (laboratory topic)
- Types of thermometer and their usage, body and skin temperature measurement (laboratory topic)
c. Hematological and Immunological System:
- Stokes Law (Erythrocytes Sedimentation Rate test) (laboratory topic)

11. Immunology and Haematology:
a. Hematological and Immunological System:
- Anemia: Aplastic anemia in adult, nutritional deficiency anemia in adult, haemolytic anemia in adult, anemia of chronic disease in adult 
- Bleeding disorders in adult: ITP, and DIC
- Coagulation disorders in adult: Thrombosis (DVT, and Pulmonary embolism)
- MPD (Myeloproliferative Disorder) in adult
- MDS (Myelodysplastic Syndrome) in adult
- Leukemia in adult
- Lymphoma in adult
- Blood transfussion in adult
- Hypersensitivity reaction
- Autoimmune disease in adult: Types of autoimmune diseases (SLE, DM type 1, Hashimoto disease, Grave disease, Myastenia Gravis)
- Immunodeficiency: Basic concept of immunopathogenesis immunodeficiency
- Secondary immunodeficiency in adult: HIV/ AIDS
- Preparing peripheral blood smear (skills laboratory topic)
- ABO and rhesus blood grouping technique (skills laboratory topic)
- Bleeding time and rumple leed test (skills laboratory topic)

12. Pediatrics:
a. Hematological and Immunological System:
- Anemia: Aplastic anemia in children, nutritional deficiency anemia in children, haemolytic anemia in children, anemia of chronic disease in children
- Clinical diagnostic for Thalassemia
- Clinical diagnostic for Haemoglobinopathy
- Bleeding disorders in children: ITP, Neonatal thrombocytopenia, and DIC
- Coagulation disorders in children: Hemophilia, and thrombosis
- MDS (Myelodysplastic Syndrome) in children
- Leukemia in children
- Lymphoma in children
- Blood transfusion in children
- Autoimmune disease in children: Types of autoimmune diseases (SLE, JRA)
- Primary immunodeficiency in children
- Secondary immunodeficiency in children: MTCT (Mother to Child Transmission), AIDS
- Immunization: Concept and basic principle of Vaccinology


*This medical syllabus copied and edited from 3 manual books for 2nd semester medical student from my university during my era. 
**The topic currently discussed for 2nd semester medical student in my university may different from this syllabus due to progression of medical knowledge and improvement of quality for medical syllabus based on my university assessment.

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