Microbiology

The purpose I share my medical syllabus during my era is to help me know the topic should I revise during my free time to improve my medical knowledge and to give an idea for future medical students about the topic they would learn in medical school.

Topic of Microbiology discussed during my time in Medical School:

A. LECTURE:

1. 1st semester:

a. Basic Science in Medicine (Mechanisms of Disease and Physiological Responses):

- Introduction and history of microorganism

- Bacterial morphology, structure, physiology and metabolism

- Pathogenesis of bacterial infection

- Bacterial classification and taxonomy

- Bacterial genetic

- Pyogenic cocci

- Enterobacteriaceae and Pseudomonas

- Actinomycetaceae and Nocardiaceae

- Listeria and Erysipelothrix

- Spore gram-positive bacteria

- Legionella and Rickettsia

- Small rod gram-negative bacteria

- Spirochaeta and Mycoplasma

- Anaerobic bacteria

- Differentiation on characteristic between bacteria, mycoplasma and virus

- Basic characteristic, morphology, structure and classification of virus

- Rhabdoviridae and Filoviridae

- Adenoviridae and Papovaviridae

- Paramyxoviridae and Orthomyxoviridae

- Togaviridae

- Picornaviridae

- Viral reproduction and interaction between virus and cell

- Classification and structure of fungi

- Coccidiodomycosis and Paracoccidiodomycosis

- Phaeohypomycosis and Hyalohypomycosis

- Fungi of systemic mycosis infection (Histoplasma, Blastomyces)

- Cryptococcus neoformans

- Nosocomial infection

- Opportunistic infection

- Immunity mechanism over microbial infection

- Vibrionaceae

b. Basic Science in Medicine (Diagnosis and Therapy/ Intervention at Cellular/ Molecular Level):

- Sampling the microbial specimen

- Bacterial colonizing procedure from clinical specimen

- Interpretation from bacterial colonizing and sensitivity test for antimicrobial drugs

2. 3rd semester:

a. Reproductive system:

- Infection in pregnancy: Bacterial infection, viral infection

b. Growth and Development:

-  Factor that affecting growth and development of children: Pathogenic microorganism during growth and development (bacteria, virus, fungi)

3. 4th semester:

a. Cardiovascular System:

- Microorganism of cardiovascular disease: Pyogenic cocci (Staphylococcus aureus, streptococcus hemolyticus, steptococcus pneumoniae), corynebacterium diphteriae, enterovirus (coxsackie virus A and B), candida (systemic infection), aspergillus

b. Respiratory System:

- Microorganism of respiratory tract infection: Pyogenic cocci (Steptococcus pneumoniae, Streptococcus group A, Staphylococcus spp), enterobacteriaceae (Klebsiella pneumoniae), Chlamydia and Mycoplasma (C. pneumoniae, M. pneumoniae), Legionellaceae (L. pneumophila), Rickettsiaceae (Coxiella burnetti), small rod gram bacteria (Hemophillus influenza)

4. 5th semester:

a. Genitourinary System:

- Microorganism of urinary tract infection: Gram negative rod bacteria (E. coli, Klebsiella, Enterobacter, Proteus species, Pseudomonas aeruginosa), gram positive cocci (Staphylococcus species, Streptococcus species), Fungi (Candida albicans)

- Pathogenesis of urinary tract infection

- Laboratory investigation and diagnostic laboratory test of urinary tract infection

- Microorganism of sexually transmitted infection: Bacteria (Pyogenic cocci-N. gonorrhoeae, Treponema pallidum, Haemophillus ducreyi, Chlamydia trachomatis, C. trachomatis-Lymphogranuloma venerum, Calymmato bacterium granulomatis-Granuloma inguinale), virus (Herpesviridae-HSV, Papovaviridae-genital warts, Hepatitis B&C), fungal (candida)

b. Gastrointestinal System:

- Bacterial infection in digestive system: Pyogenic cocci (Staphylococcus aureus), Enterobacteriaceae (Salmonella, Shigella, Yersinia, E. coli, Enteropathogen, Klebsiella, Citobacter, Enterobacter), Vibrionaceace (V. cholera, V. parahemolyticuc, V. vulnificus), Campylobacter (C. jejuni), Helicobacter (H. pylori), Bacillaceae (B. cereus, Cl. perfringens, Cl. botulinum, Cl. difficile)

- Viral infection in digestive system: Rotavirus, Narwalk virus, Calici virus, Hepatitis A virus

- Fungi infection in digestive system: C. albicans, C. parapsilosis, Actinomyces israelia, Aspergilus species, Trichoderma species, Paecilomyces variotii

c. Special Senses System:

- Viral ocular infection

- Bacterial ocular infection

- Fungal ocular infection

- Virus in ENT infective cases: Rhinovirus, paramyxovirus, respiratory syncytial virus (laryngotracheobronchitis), orthomyxovirus, echovirus, coxsackie virus, corona virus

- Bacteria in ENT infective cases: pseudomonas, staphylococcus aureus, streptococcus pyogenes, streptococcus pneumoniae, H. influenzae, anaerobe infection (Fusobacterium, Klebsiella ozaenae, Moraxella catarrhalis)

- Fungi in ENT infective cases: Candida, Rhinosporidiosis

5. 6th semester:

a. Brain and Mind System:

- Microbes in central nervous system infection: Purulent meningitis (Pyogenic cocci - N. meningitidis & S. pneumoniae, type B Hemophilus influenza, Stapylococcus aureus, Listeria monocytogenes), granulomatous meningitis (Mycobacterium tuberculosis - tuberculous meningitis, Treponema pallidum, Cryptococcus neoformans, Coccidioides immitis, Histoplasma capsulatum), aseptic meningitis (Poliovirus, Coxackie virus - Enterocytophatic human orphan, Herpes simplex, Paramyxovirus - mumps, Rhabdovirus - rabies virus, Leptospira, Clostridium tetani), encephalitis (Togavirus - Chikungunya & other Arbovirus, Flavivirus, Rabies virus, HIV virus), neurotoxins-producing microbes (Clostridium tetani - tetanospasmin, Clostridium botulinum), brain abscess (Streptococcus species, Staphylococcus aureus, Enterobacteriaceae, Bacterioides)

6. 7th semester:

a. Tropical Medicine:

- Bacterial zoonotic disease: Leptospirosis, bucellosis, tularemia, plaque, yersiniosis, bacterial cellulitis, cat bite, dog bite, anthrax, psittacosis, ornitosis, non-typhoidal salmonella, lyme disease, melioidosis, cat scratch, bartonelosis, spotted fever, Q fever, erlichiosis, aeromanas infection, erysepeloid, listeriosis, mycobacterial infection (M. bovis, M. avium), campylobacter jejuni

- Viral zoonotic disease: Rabies, hantavirus, pulmonary syndrome (pneumonia), yellow fever, dengue, encephalitis

b. Elective (Tropical Infectious Disease):

- Determinant of tuberculosis case definition 

- Detection, classification and type of tuberculosis cases

- Management of non-compliance to anti-tuberculosis medication cases

- Management of tuberculosis in specific health condition

- Recording and reporting in National tuberculosis management program

- Indicator in tuberculosis program and method of indicator analysis: Case detection rate, success rate

c. Basic Biomedical Science in Elective:

- Sampling technique and sending technique of the microbiological specimen

- Antimicrobial sensitivity test and antimicrobial resistancy

- Nosocomial infection

- Body immunity to bacteria, virus and fungus

B. LABORATORY:

1. 1st semester:

a. Basic Science in Medicine (Mechanisms of Disease and Physiological Responses):

- Demostration of laboratory apparatus, introduction to sterilization technique and growth media for bacteria and fungi (wet laboratory)

- Normal flora, growth and contaminant (wet laboratory)

- Aerobic rod Gram positive bacteria (wet laboratory)

- Anaerobic bacteria (wet laboratory)

- Pyogenic cocci (dry laboratory)

- Enterobacteriaceae and vibrionaceae (dry laboratory)

- Sensitivity test for antimicrobial drugs (dry laboratory)

2. 5th semester:

a. Gastrointestinal System:

- Enterobacteriaceae

3. 7th semester:

a. Basic Biomedical Science in Elective:

- Sampling technique of acid-fast bacteria (Ziehl Neelsen method) with International Union Against Tuberculosis and Lung Disease (IUATLD) scale

C. SKILLS LABORATORY (OSCE):

1. 4th semester:

a. Respiratory System:

- Staining of acid-fast bacteria (bacillus) with Zielh Neelsen technique

- Staining of bacteria with Gram staining technique

D. TUTORIAL:

1. 4th semester:

a. Respiratory System:

- Mycobacteriaceae (M. tuberculosis)

*This medical syllabus copied and edited from 2 manual books for 1st semester medical student, 2 manual books for 3rd semester medical student, 2 manual books for 4th semester medical student, 3 manual books for 5th semester medical student, 1 manual book for 6th semester medical student and 2 manual books for 7th semester medical student from my university during my era. 
**The topic currently discussed in my university may different from this syllabus due to progression of medical knowledge and improvement of quality for medical syllabus based on my university assessment.